RESUMO
Background Vaccination acts by boosting the capacity of a person's immune system to identify and effectively resist infection-causing bacteria and viruses, as it stimulates the immune system to respond to the vaccine's antigens. The immunological response may include local and systemic symptoms, including pain at the injection site and fever, respectively. The Sinovac vaccine is an inactivated virus vaccine made in China and is one of the most widely used vaccines in many countries; however, the side effects of the Sinovac vaccine have not been well-studied in our population. Therefore, this study assessed the prevalence of side effects experienced by participants after receiving the Sinovac vaccine. Methodology This multicenter, cross-sectional study was conducted using a non-probability sampling method. The duration of the study was six months from May 1, 2022, to October 31, 2022. A total of 800 participants who were completely vaccinated with the Sinovac vaccine were included in the study. For categorical data, frequencies and percentages were documented, while for continuous data, such as age, height, weight, and the duration of comorbidities, means and standard deviations were evaluated. Results The study findings showed that out of 800 participants, 534 (66.8%) were males and 266 (33.3%) were females, with a mean age of 41.20 ± 13.70 years. Among them, 162 (20.3%) had hypertension, and 104 (13.0%) had diabetes. Following the first dose of the Sinovac vaccine, fever was the most commonly reported side effect in 350 (43.8%) participants. Additionally, pain at the injection site in 238 (29.8%) participants, followed by swelling at the injection site in 228 (28.5%) recipients, were among other common side effects. Following the second dose of the Sinovac vaccine, fever was the most commonly reported side effect in 262 (32.8%) participants. Conclusions This study concluded that fever was the most frequent systemic side effect, whereas pain and swelling at the injection site were the most frequent local side effects following the administration of the first and second doses of the Sinovac vaccine. Both dosages of Sinovac were well-tolerated, and the majority of the adverse effects were minor and self-limiting.
RESUMO
Pakistan is included in top 50 countries which are estimated to face serious agriculture and food deficiency related challenges due to the worldwide pandemic coronavirus 2019 (COVID-19). The aim of this study was to evaluate the effects of COVID-19 on food supply chain and agriculture in Punjab, Pakistan, by using space-time scan statistic (STSS). A survey was conducted at 720 points in different districts of the province. The STSS detected "active" and emerging clusters that are current at the end of our study area-particularly, 17 clusters were formed while adding the updated case data. Software ArcGIS 10.3 was used to find relative risk (RR) values; the maximum RR value was found to be 42.19 and maximum observed cases 53,265 during June 15-July 1, 2020. It was not always necessary that if the number of active cases in Punjab increased, there should be higher relative risk for more number of districts and vice versa. Due to the highest number of cases of COVID-19 and RR values during July, mostly farmers faced many difficulties during the cultivation of cotton and rice. Mostly farmers (72%) observed increase in prices of inputs (fertilizers and pesticides) during lockdown. If the supply chain of agriculture related inputs is disturbed, farmers may find it quite difficult to access markets, which could result in a decline in production and sales of crops and livestock in study area. It is suggested that to protect the food security and to decrease the effect of the lockdown, Punjab government needs to review food policy and analyse how market forces will respond to the imbalanced storage facilities and capacity, supply and demand and price control of products. The findings of this study can also help policy-makers to formulate an effective food security and agriculture adaptation strategy.
RESUMO
Coronavirus disease (COVID)-19 is a viral and transferable disease caused by severe respiratory syndrome-coronavirus-2. It can spread through breathing droplets in human beings. It caused 5.32 million deaths around the world at the end of 2021. COVID-19 has caused several positive impacts as well, such as a reduction in air, water, and noise pollution. However, its negative impacts are by far critical such as increased death rate, increased release of microcontaminants (pesticides, biocides, pharmaceuticals, surfactants, polycyclic aromatic hydrocarbons (PAHs), flame retardants, and heavy metals), increased biomedical waste generation due to excessive use of safety equipment and its disposal, and municipal solid waste generation. Environmental pollution was significantly reduced due to lockdown during the COVID-19 period. Therefore, the quality of air and water improved. COVID-19 affected all sections of the population, particularly the most vulnerable members of society, and thus pushed more people into poverty. At the world level, it increased risks to food safety by increasing prices and lowering revenues, forcing households to reduce their food consumption in terms of quantity and quality. COVID-19 also upset various exercises e.g., horticulture, fisheries, domesticated animals, and agribusiness hence prohibiting the development of merchandise for poor-country ranchers. Most of the patients can self-recover from COVID-19 if they do not have any other diseases like high blood pressure, diabetes, and heart problems. Predictably, the appropriate execution of the proposed approaches (vaccination, wearing face masks, social distancing, sustainable industrialization) is helpful for worldwide environmental sustainability.